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TCR repertoire and Foxp3 expression define functionally distinct subsets of CD4(+) T(reg) cells

Despite extensive research efforts to characterize peripheral regulatory T cells (T(reg)) expressing transcription factor Foxp3, their subset complexity, phenotypic characteristics, TCR repertoire and antigen specificities remain ambiguous. Here, we identify and define two subsets of peripheral T(re...

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Autori principali: Kuczma, Michal, Pawlikowska, Iwona, Kopij, Magdalena, Podolsky, Robert, Rempala, Grzegorz A., Kraj, Piotr
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804979/
https://ncbi.nlm.nih.gov/pubmed/19648277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900514
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