Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3(+) T(reg) Cells

Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and self-renewal of multiple tissues. We show that signaling through the bone morphogenic protein receptor 1α (BMPR1α) sustains expression of FOXP3 in T(re...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Browning, Lauren M., Miller, Caroline, Kuczma, Michal, Pietrzak, Maciej, Jing, Yu, Rempala, Grzegorz, Muranski, Pawel, Ignatowicz, Leszek, Kraj, Piotr
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602518/
https://ncbi.nlm.nih.gov/pubmed/33027660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108219
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