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Altered connexin 43 expression underlies age dependent decrease of T(reg) cell suppressor function in NOD mice

Type I diabetes (T1D) is one of the most extensively studied autoimmune diseases but the cellular and molecular mechanisms leading to T cell-mediated destruction of insulin-producing β-cells are still not well understood. Here we show that T(reg) cells in NOD mice undergo age-dependent loss of suppr...

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Publicado en:J Immunol
Main Authors: Kuczma, Michal, Wang, Cong-Yi, Ignatowicz, Leszek, Gourdie, Robert, Kraj, Piotr
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465104/
https://ncbi.nlm.nih.gov/pubmed/25911751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400887
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