TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease with worldwide high prevalence. Although AS is strongly associated with HLA-B27 MHC-I antigen presentation, the role played by αβ T cells in AS remains elusive. METHODS: Utilizing TCRβ repertoire sequencing and bioinformatics...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zheng, Ming, Zhang, Xin, Zhou, Yinghui, Tang, Juan, Han, Qing, Zhang, Yang, Ni, Qingshan, Chen, Gang, Jia, Qingzhu, Yu, Haili, Liu, Siqi, Robins, Elizabeth, Jiang, Ning Jenny, Wan, Ying, Li, Qi-Jing, Chen, Zhi-Nan, Zhu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796593/
https://ncbi.nlm.nih.gov/pubmed/31477563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.032
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