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Deep sequencing of the human TCRγ and TCRβ repertoires provides evidence that TCRβ rearranges after αβ, γδ T-cell commitment

The two main lineages of T lymphocytes develop from multi potent precursors in the human thymus. The most common type in blood are αβ T cells, which bind to antigenic peptides displayed on the surface of cells by human leukocyte antigen (HLA) molecules. Far less well understood are γδ T cells, which...

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Autors principals: Sherwood, Anna M., Desmarais, Cindy, Livingston, Robert J., Andriesen, Jessica, Haussler, Maximilian, Carlson, Christopher S., Robins, Harlan
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179204/
https://ncbi.nlm.nih.gov/pubmed/21734177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002536
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