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Massively parallel interrogation and mining of natively paired human TCRαβ repertoires
T cells engineered to express antigen-specific T cell receptors (TCRs) are potent therapies for viral infections and cancer. However, efficient identification of clinical candidate TCRs is complicated by the size and complexity of T cell repertoires and the challenges of working with primary T cells...
Kaydedildi:
| Yayımlandı: | Nat Biotechnol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7224336/ https://ncbi.nlm.nih.gov/pubmed/32393905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0438-y |
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