TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease with worldwide high prevalence. Although AS is strongly associated with HLA-B27 MHC-I antigen presentation, the role played by αβ T cells in AS remains elusive. METHODS: Utilizing TCRβ repertoire sequencing and bioinformatics...

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Vydáno v:EBioMedicine
Hlavní autoři: Zheng, Ming, Zhang, Xin, Zhou, Yinghui, Tang, Juan, Han, Qing, Zhang, Yang, Ni, Qingshan, Chen, Gang, Jia, Qingzhu, Yu, Haili, Liu, Siqi, Robins, Elizabeth, Jiang, Ning Jenny, Wan, Ying, Li, Qi-Jing, Chen, Zhi-Nan, Zhu, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796593/
https://ncbi.nlm.nih.gov/pubmed/31477563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.032
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