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T Cell Receptor CDR3 Sequence but Not Recognition Characteristics Distinguish Autoreactive Effector and Foxp3(+) Regulatory T Cells

The source, specificity, and plasticity of the forkhead box transcription factor 3 (Foxp3)(+) regulatory T (Treg) and conventional T (Tconv) cell populations active at sites of autoimmune pathology are not well characterized. To evaluate this, we combined global repertoire analyses and functional as...

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Detalhes bibliográficos
Main Authors: Liu, Xin, Nguyen, Phuong, Liu, Wei, Cheng, Cheng, Steeves, Meredith, Obenauer, John C., Ma, Jing, Geiger, Terrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878844/
https://ncbi.nlm.nih.gov/pubmed/20005134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.023
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