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Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3(+) regulatory T lymphocytes in MOG-EAE
Regulatory T lymphocytes (Treg) expressing the Forkhead Box Transcription Factor 3 (Foxp3) are critical modulators of autoimmunity. Foxp3(+) Treg may develop in the thymus as a population distinct from conventional Foxp3(−) αβ T cells (Tconv). Alternatively, plasticity in Foxp3 expression may allow...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944006/ https://ncbi.nlm.nih.gov/pubmed/20810983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001550 |
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