LACK OF ANALGESIC EFFICACY OF SPINAL ONDANSETRON ON THERMAL AND MECHANICAL HYPERSENSITIVITY FOLLOWING SPINAL NERVE LIGATION IN THE RAT

The balance between descending inhibition and facilitation is thought to be disturbed in chronic pain states. Increased facilitation by spinally released serotonin has been suggested by demonstration that mechanically evoked neuronal responses of wide dynamic range neurons are inhibited by 5-HT3 rec...

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Hauptverfasser: Peters, Christopher M., Hayashida, Ken-ichiro, Ewan, Eric E., Nakajima, Kunie, Obata, Hideaki, Xu, Qinghao, Yaksh, Tony L., Eisenach, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943762/
https://ncbi.nlm.nih.gov/pubmed/20637741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.07.020
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