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Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain
BACKGROUND: Gabapentin recruits descending inhibition to produce analgesia after nerve injury, but whether this is a local action in the brainstem is unknown. The authors hypothesized that gabapentin activates noradrenergic neurons in the locus coeruleus (LC) by a local action. METHODS: Male rats un...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843419/ https://ncbi.nlm.nih.gov/pubmed/19034104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31818dac9c |
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