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Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms

Gabapentin has shown to be effective in animals and humans with acute postoperative and chronic pain. Yet the mechanisms by which gabapentin reduces pain have not been fully addressed. The current study performed in vivo microdialysis in the locus coeruleus (LC) in normal and spinal nerve ligated (S...

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Bibliografische gegevens
Hoofdauteurs: Suto, Takashi, Severino, Amie L., Eisenach, James C., Hayashida, Ken-ichiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992194/
https://ncbi.nlm.nih.gov/pubmed/24495399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.01.040
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