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Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats

Descending noradrenergic inhibition is an important endogenous pain-relief mechanism which can be activated by local glutamate signaling. In the present study, we examined the effect of glutamate transporter activation by riluzole in the regulation of activity of locus coeruleus (LC) neurons, which...

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Detalhes bibliográficos
Main Authors: Hayashida, Ken-ichiro, Parker, Renee A., Eisenach, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822016/
https://ncbi.nlm.nih.gov/pubmed/20059984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.12.086
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