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Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats

Descending noradrenergic inhibition is an important endogenous pain-relief mechanism which can be activated by local glutamate signaling. In the present study, we examined the effect of glutamate transporter activation by riluzole in the regulation of activity of locus coeruleus (LC) neurons, which...

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Bibliographic Details
Main Authors: Hayashida, Ken-ichiro, Parker, Renee A., Eisenach, James C.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822016/
https://ncbi.nlm.nih.gov/pubmed/20059984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.12.086
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