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Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury

The present study examined whether the histone deacetylase inhibitor valproate prevents down-regulation of glutamate transporters in the primary cultured astrocytes and in the spinal cord after L5-L6 spinal nerve ligation (SNL), and whether this action of valproate on spinal glutamate transporters p...

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Hlavní autoři: Yoshizumi, Masaru, Eisenach, James. C., Hayashida, Ken-ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818435/
https://ncbi.nlm.nih.gov/pubmed/24021575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.07.007
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