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Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury
The present study examined whether the histone deacetylase inhibitor valproate prevents down-regulation of glutamate transporters in the primary cultured astrocytes and in the spinal cord after L5-L6 spinal nerve ligation (SNL), and whether this action of valproate on spinal glutamate transporters p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818435/ https://ncbi.nlm.nih.gov/pubmed/24021575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.07.007 |
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