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Natural mutagenesis of human genomes by endogenous retrotransposons

Two abundant classes of mobile elements, namely Alu and L1 elements, continue to generate new retrotransposon insertions in human genomes. Estimates suggest that these elements have generated millions of new germline insertions in individual human genomes worldwide. Unfortunately, current technologi...

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Autors principals: Iskow, Rebecca C., McCabe, Michael T., Mills, Ryan E., Torene, Spencer, Pittard, W. Stephen, Neuwald, Andrew F., Van Meir, Erwin G., Vertino, Paula M., Devine, Scott E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943760/
https://ncbi.nlm.nih.gov/pubmed/20603005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.020
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