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Mutagenesis in rodents using the L1 retrotransposon
LINE1 (L1) retrotransposons are genetic elements that are present in all mammalian genomes. L1s are active in both humans and mice, and are capable of copying themselves and inserting the copy into a new genomic location. These de novo insertions occasionally result in disease. Endogenous L1 retrotr...
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| Format: | Artigo |
| Sprache: | Inglês |
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BioMed Central
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2106842/ https://ncbi.nlm.nih.gov/pubmed/18047693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s16 |
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