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Natural mutagenesis of human genomes by endogenous retrotransposons

Two abundant classes of mobile elements, namely Alu and L1 elements, continue to generate new retrotransposon insertions in human genomes. Estimates suggest that these elements have generated millions of new germline insertions in individual human genomes worldwide. Unfortunately, current technologi...

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Bibliografski detalji
Glavni autori: Iskow, Rebecca C., McCabe, Michael T., Mills, Ryan E., Torene, Spencer, Pittard, W. Stephen, Neuwald, Andrew F., Van Meir, Erwin G., Vertino, Paula M., Devine, Scott E.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943760/
https://ncbi.nlm.nih.gov/pubmed/20603005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.020
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