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Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers

β-amyloid (Aβ) is the main protein component of the amyloid plaques associated with Alzheimer’s disease. Transthyretin (TTR) is a homotetramer that circulates in both blood and cerebrospinal fluid. Wild-type transthyretin (TTR) amyloid deposits are linked to senile systemic amyloidosis, a common dis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Du, Jiali, Murphy, Regina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943652/
https://ncbi.nlm.nih.gov/pubmed/20795734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101280t
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