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Metnase promotes restart and repair of stalled and collapsed replication forks
Metnase is a human protein with methylase (SET) and nuclease domains that is widely expressed, especially in proliferating tissues. Metnase promotes non-homologous end-joining (NHEJ), and knockdown causes mild hypersensitivity to ionizing radiation. Metnase also promotes plasmid and viral DNA integr...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943610/ https://ncbi.nlm.nih.gov/pubmed/20457750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq339 |
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