Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes.

Metabolic acidosis often leads to loss of body protein due mainly to accelerated protein breakdown in muscle. To identify which proteolytic pathway is activated, we measured protein degradation in incubated epitrochlearis muscles from acidotic (NH4Cl-treated) and pair-fed rats under conditions that...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Mitch, W E, Medina, R, Grieber, S, May, R C, England, B K, Price, S R, Bailey, J L, Goldberg, A L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117208
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!