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Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes.

Metabolic acidosis often leads to loss of body protein due mainly to accelerated protein breakdown in muscle. To identify which proteolytic pathway is activated, we measured protein degradation in incubated epitrochlearis muscles from acidotic (NH4Cl-treated) and pair-fed rats under conditions that...

詳細記述

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書誌詳細
主要な著者: Mitch, W E, Medina, R, Grieber, S, May, R C, England, B K, Price, S R, Bailey, J L, Goldberg, A L
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC294343/
https://ncbi.nlm.nih.gov/pubmed/8182144
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