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Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis.

Chronic renal failure (CRF) is associated with metabolic acidosis and abnormal muscle protein metabolism. As we have shown that acidosis by itself stimulates muscle protein degradation by a glucocorticoid-dependent mechanism, we assessed the contribution of acidosis to changes in muscle protein turn...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: May, R C, Kelly, R A, Mitch, W E
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1987
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3549778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112924
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