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PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps

Translocation of helicase-like proteins on nucleic acids underlies key cellular functions. However, it is still unclear how translocation can drive removal of DNA bound proteins, and basic properties like the elementary step size remain controversial. Using single molecule fluorescence analysis on a...

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Detalhes bibliográficos
Main Authors: Park, Jeehae, Myong, Sua, Niedziela-Majka, Anita, Yu, Jin, Lohman, Timothy M., Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943210/
https://ncbi.nlm.nih.gov/pubmed/20723756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.016
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