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DNA Helicase Activity of PcrA Is Not Required for the Displacement of RecA Protein from DNA or Inhibition of RecA-Mediated Strand Exchange

PcrA is a conserved DNA helicase present in all gram-positive bacteria. Bacteria lacking PcrA show high levels of recombination. Lethality induced by PcrA depletion can be overcome by suppressor mutations in the recombination genes recFOR. RecFOR proteins load RecA onto single-stranded DNA during re...

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Bibliografische gegevens
Hoofdauteurs: Anand, Syam P., Zheng, Haocheng, Bianco, Piero R., Leuba, Sanford H., Khan, Saleem A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913354/
https://ncbi.nlm.nih.gov/pubmed/17449621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00376-07
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