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DNA Helicase Activity of PcrA Is Not Required for the Displacement of RecA Protein from DNA or Inhibition of RecA-Mediated Strand Exchange

PcrA is a conserved DNA helicase present in all gram-positive bacteria. Bacteria lacking PcrA show high levels of recombination. Lethality induced by PcrA depletion can be overcome by suppressor mutations in the recombination genes recFOR. RecFOR proteins load RecA onto single-stranded DNA during re...

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Main Authors: Anand, Syam P., Zheng, Haocheng, Bianco, Piero R., Leuba, Sanford H., Khan, Saleem A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913354/
https://ncbi.nlm.nih.gov/pubmed/17449621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00376-07
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