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DNA Helicase Activity of PcrA Is Not Required for the Displacement of RecA Protein from DNA or Inhibition of RecA-Mediated Strand Exchange

PcrA is a conserved DNA helicase present in all gram-positive bacteria. Bacteria lacking PcrA show high levels of recombination. Lethality induced by PcrA depletion can be overcome by suppressor mutations in the recombination genes recFOR. RecFOR proteins load RecA onto single-stranded DNA during re...

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Detalhes bibliográficos
Main Authors: Anand, Syam P., Zheng, Haocheng, Bianco, Piero R., Leuba, Sanford H., Khan, Saleem A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913354/
https://ncbi.nlm.nih.gov/pubmed/17449621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00376-07
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