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DNA Helicase Activity of PcrA Is Not Required for the Displacement of RecA Protein from DNA or Inhibition of RecA-Mediated Strand Exchange

PcrA is a conserved DNA helicase present in all gram-positive bacteria. Bacteria lacking PcrA show high levels of recombination. Lethality induced by PcrA depletion can be overcome by suppressor mutations in the recombination genes recFOR. RecFOR proteins load RecA onto single-stranded DNA during re...

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Autors principals: Anand, Syam P., Zheng, Haocheng, Bianco, Piero R., Leuba, Sanford H., Khan, Saleem A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913354/
https://ncbi.nlm.nih.gov/pubmed/17449621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00376-07
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