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PcrA-mediated disruption of RecA nucleoprotein filaments—essential role of the ATPase activity of RecA
The essential DNA helicase, PcrA, regulates recombination by displacing the recombinase RecA from the DNA. The nucleotide-bound state of RecA determines the stability of its nucleoprotein filaments. Using single-molecule fluorescence approaches, we demonstrate that RecA displacement by a translocati...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458574/ https://ncbi.nlm.nih.gov/pubmed/22743269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks641 |
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