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A 5′-to-3′ strand exchange polarity is intrinsic to RecA nucleoprotein filaments in the absence of ATP hydrolysis

RecA is essential to recombinational DNA repair in which RecA filaments mediate the homologous DNA pairing and strand exchange. Both RecA filament assembly and the subsequent DNA strand exchange are directional. Here, we demonstrate that the polarity of DNA strand exchange is embedded within RecA fi...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Lin, Yu-Hsuan, Chu, Chia-Chieh, Fan, Hsiu-Fang, Wang, Pang-Yen, Cox, Michael M, Li, Hung-Wen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547424/
https://ncbi.nlm.nih.gov/pubmed/30916331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz189
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