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RecA-mediated SOS induction requires an extended filament conformation but no ATP hydrolysis

The Escherichia coli SOS response to DNA damage is modulated by the RecA protein, a recombinase that forms an extended filament on single-stranded DNA and hydrolyzes ATP. The RecA K72R (recA2201) mutation eliminates the ATPase activity of RecA protein. The mutation also limits the capacity of RecA t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gruenig, Marielle C., Renzette, Nicholas, Long, Edward, Chitteni-Pattu, Sindhu, Inman, Ross B., Cox, Michael M., Sandler, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538424/
https://ncbi.nlm.nih.gov/pubmed/18627467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06341.x
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