Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability

RecA proteins form a long stable filament on a single-stranded DNA and catalyze strand exchange reaction. The stability of RecA filament changes dramatically with pH, yet its detailed mechanism is not known. Here, using a single molecule assay, we determined the binding and dissociation rates of Rec...

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Udgivet i:PLoS One
Main Authors: Kim, Sung Hyun, Park, Jeehae, Joo, Chirlmin, Kim, Doseok, Ha, Taekjip
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301630/
https://ncbi.nlm.nih.gov/pubmed/25608006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115611
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