Laddar...

Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments

BACKGROUND: Inclusions of TAR DNA binding protein-43 (TDP-43) are the defining histopathological feature of several neurodegenerative diseases collectively referred to as TDP-43 proteinopathies. These diseases are characterized by the presence of cellular aggregates composed of abnormally phosphoryl...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Yong-Jie, Gendron, Tania F, Xu, Ya-Fei, Ko, Li-Wen, Yen, Shu-Hui, Petrucelli, Leonard
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941488/
https://ncbi.nlm.nih.gov/pubmed/20804554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-33
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!