Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.

Pancreatic beta-cell function was studied in six subjects with mutations in the enzyme glucokinase (GCK) who were found to have elevated fasting and postprandial glucose levels in comparison to six normoglycemic controls. Insulin secretion rates (ISRs) were estimated by deconvolution of peripheral C...

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Autores principales: Byrne, M M, Sturis, J, Clément, K, Vionnet, N, Pueyo, M E, Stoffel, M, Takeda, J, Passa, P, Cohen, D, Bell, G I
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC294056/
https://ncbi.nlm.nih.gov/pubmed/8132752
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