Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.

Pancreatic beta-cell function was studied in six subjects with mutations in the enzyme glucokinase (GCK) who were found to have elevated fasting and postprandial glucose levels in comparison to six normoglycemic controls. Insulin secretion rates (ISRs) were estimated by deconvolution of peripheral C...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Byrne, M M, Sturis, J, Clément, K, Vionnet, N, Pueyo, M E, Stoffel, M, Takeda, J, Passa, P, Cohen, D, Bell, G I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294056/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117064
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