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Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus.

Normal subjects demonstrate the presence of ultradian oscillations (period 80-150 min) in insulin secretion rate (ISR) tightly coupled to glucose oscillations of similar period. These oscillations appear to be a function of the feedback loop linking glucose and insulin. The present study was underta...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: O'Meara, N M, Sturis, J, Van Cauter, E, Polonsky, K S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8325993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116560
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