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MiRNAs Regulating Insulin Sensitivity Are Dysregulated in Polycystic Ovary Syndrome (PCOS) Ovaries and Are Associated With Markers of Inflammation and Insulin Sensitivity

Objective: MicroRNAs (miRNAs) are gene expression regulators. Altered miRNA levels are associated with diabetes, insulin resistance, and inflammation. Insulin resistance and inflammation are both features of Polycystic ovary syndrome (PCOS). The aim of this study was first to assess differences in s...

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Autori principali: Francesca Cirillo, Cecilia Catellani, Pietro Lazzeroni, Chiara Sartori, Alessia Nicoli, Sergio Amarri, Giovanni Battista La Sala, Maria Elisabeth Street
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-12-01
Serie:Frontiers in Endocrinology
Soggetti:
miRNA
PCOS
inflammation
HMGB1
insulin resistance
estradiol
Accesso online:https://www.frontiersin.org/article/10.3389/fendo.2019.00879/full
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