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FoxO1 Links Hepatic Insulin Action to Endoplasmic Reticulum Stress
Forkhead box O1 (FoxO1) is a transcription factor that mediates the inhibitory effect of insulin on target genes in hepatic metabolism. Hepatic FoxO1 activity is up-regulated to promote glucose production during fasting and is suppressed to limit postprandial glucose excursion after meals. Increased...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Endocrine Society
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940535/ https://ncbi.nlm.nih.gov/pubmed/20501674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1306 |
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