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FOXO1 Mediates the Autocrine Effect of Endothelin-1 on Endothelial Cell Survival

Chronic hyperglycemia exerts a deleterious effect on endothelium, contributing to endothelial dysfunction and microvascular complications in poorly controlled diabetes. To understand the underlying mechanism, we studied the effect of endothelin-1 (ET-1) on endothelial production of Forkhead box O1 (...

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Main Authors: Cifarelli, Vincenza, Lee, Sojin, Kim, Dae Hyun, Zhang, Ting, Kamagate, Adama, Slusher, Sandra, Bertera, Suzanne, Luppi, Patrizia, Trucco, Massimo, Dong, H. Henry
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385789/
https://ncbi.nlm.nih.gov/pubmed/22570335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1276
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