FoxO1 Links Hepatic Insulin Action to Endoplasmic Reticulum Stress

Forkhead box O1 (FoxO1) is a transcription factor that mediates the inhibitory effect of insulin on target genes in hepatic metabolism. Hepatic FoxO1 activity is up-regulated to promote glucose production during fasting and is suppressed to limit postprandial glucose excursion after meals. Increased...

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Hlavní autoři: Kamagate, Adama, Kim, Dae Hyun, Zhang, Ting, Slusher, Sandra, Gramignoli, Roberto, Strom, Stephen C., Bertera, Suzanne, Ringquist, Steven, Dong, H. Henry
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940535/
https://ncbi.nlm.nih.gov/pubmed/20501674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1306
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