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PPARα mediates the hypolipidemic action of fibrates by antagonizing FoxO1
High-fructose consumption is associated with insulin resistance and diabetic dyslipidemia, but the underlying mechanism is unclear. We show in hamsters that high-fructose feeding stimulated forkhead box O1 (FoxO1) production and promoted its nuclear redistribution in liver, correlating with augmente...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665003/ https://ncbi.nlm.nih.gov/pubmed/16985262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00157.2006 |
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