PPARα mediates the hypolipidemic action of fibrates by antagonizing FoxO1

High-fructose consumption is associated with insulin resistance and diabetic dyslipidemia, but the underlying mechanism is unclear. We show in hamsters that high-fructose feeding stimulated forkhead box O1 (FoxO1) production and promoted its nuclear redistribution in liver, correlating with augmente...

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Bibliographic Details
Main Authors: Qu, Shen, Su, Dongming, Altomonte, Jennifer, Kamagate, Adama, He, Jing, Perdomo, German, Tse, Tonia, Jiang, Yu, Dong, H. Henry
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665003/
https://ncbi.nlm.nih.gov/pubmed/16985262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00157.2006
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