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FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice
Excessive production of triglyceride-rich VLDL is attributable to hypertriglyceridemia. VLDL production is facilitated by microsomal triglyceride transfer protein (MTP) in a rate-limiting step that is regulated by insulin. To characterize the underlying mechanism, we studied hepatic MTP regulation b...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391277/ https://ncbi.nlm.nih.gov/pubmed/18497885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32914 |
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