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Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase

Coordinate regulation of PARPs-1/2 and PARG is required for cellular responses to genotoxic stress. While PARPs-1/2 are regulated by DNA breaks and covalent modifications, mechanisms of PARG regulation are poorly understood. We report here discovery of a PARG regulatory segment far removed linearly...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Botta, Davide, Jacobson, Myron K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939713/
https://ncbi.nlm.nih.gov/pubmed/20684510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100973m
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