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Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase
Coordinate regulation of PARPs-1/2 and PARG is required for cellular responses to genotoxic stress. While PARPs-1/2 are regulated by DNA breaks and covalent modifications, mechanisms of PARG regulation are poorly understood. We report here discovery of a PARG regulatory segment far removed linearly...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939713/ https://ncbi.nlm.nih.gov/pubmed/20684510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100973m |
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