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Reversible, Allosteric Small-Molecule Inhibitors of Regulator of G Protein Signaling Proteins
Regulators of G protein signaling (RGS) proteins are potent negative modulators of G protein signaling and have been proposed as potential targets for small-molecule inhibitor development. We report a high-throughput time-resolved fluorescence resonance energy transfer screen to identify inhibitors...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental
Therapeutics
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939488/ https://ncbi.nlm.nih.gov/pubmed/20571077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.065128 |
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