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Suppression of HLA Expression by Lentivirus-mediated Gene Transfer of siRNA Cassettes and In Vivo Chemoselection to Enhance Hematopoietic Stem Cell Transplantation

Current approaches for hematopoietic stem cell (HSC) and organ transplantation are limited by donor and host-mediated immune responses to allo-antigens. Application of these therapies is limited by the toxicity of preparative and post-transplant immunosuppressive regimens and a shortage of appropria...

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Detalhes bibliográficos
Main Authors: Hacke, Katrin, Falahati, Rustom, Flebbe-Rehwaldt, Linda, Kasahara, Noriyuki, Gaensler, Karin M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938774/
https://ncbi.nlm.nih.gov/pubmed/19048410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-008-8088-z
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