Identification of effective siRNA against K-ras in human pancreatic cancer cell line MiaPaCa-2 by siRNA expression cassette

AIM: We shall construct the small interfering RNA (siRNA) expression cassette (SEC) targeting activated K-ras gene sequence, identify more effective siRNA sequence against K-ras gene in human pancreatic cancer cell line MiaPaCa-2 by SEC and reveal the anti-cancer effects of RNA interference (RNAi) a...

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Dettagli Bibliografici
Pubblicato in:World J Gastroenterol
Autori principali: Wang, Wei, Wang, Chun-You, Dong, Ju-Hua, Chen, Xiong, Zhang, Min, Zhao, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2005
Soggetti:
Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305731/
https://ncbi.nlm.nih.gov/pubmed/15801000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i13.2026
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