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Exosomal lipids induce human pancreatic tumoral MiaPaCa-2 cells resistance through the CXCR4-SDF-1α signaling axis

We previously reported that exosomes secreted by human pancreatic tumor cells induce cell death through the inhibition of the Notch-1 survival pathway (Ristorcelli et al., 2009). We demonstrated that exosomal lipids evoked apoptosis of human pancreatic cancer SOJ-6 cells. Based on the lipid composit...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Beloribi-Djefaflia, Sadia, Siret, Carole, Lombardo, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341461/
https://ncbi.nlm.nih.gov/pubmed/25821841
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