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Chemoselection of Allogeneic HSC After Murine Neonatal Transplantation Without Myeloablation or Post-transplant Immunosuppression

The feasibility of allogeneic transplantation, without myeloablation or post-transplant immunosuppression, was tested using in vivo chemoselection of allogeneic hematopoietic stem cells (HSCs) after transduction with a novel tricistronic lentiviral vector (MGMT(P140K)-2A-GFP-IRES-TK (MAGIT)). This v...

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Detalhes bibliográficos
Main Authors: Falahati, Rustom, Zhang, Jianqing, Flebbe-Rehwaldt, Linda, Shi, Yimin, Gerson, Stanton L, Gaensler, Karin ML
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498795/
https://ncbi.nlm.nih.gov/pubmed/22871662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.136
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