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Autophagy, a guardian against neurodegeneration
Autophagy is an intracellular degradation process responsible for the clearance of most long-lived proteins and organelles. Cytoplasmic components are enclosed by double-membrane autophagosomes, which subsequently fuse with lysosomes for degradation. Autophagy dysfunction may contribute to the patho...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Academic Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938570/ https://ncbi.nlm.nih.gov/pubmed/20188203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.02.008 |
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