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Autophagy in neurodegeneration and development

Efficient protein turnover is essential for the maintenance of cellular health. Here we review how autophagy has fundamental functions in cellular homeostasis and possible uses as a therapeutic strategy for neurodegenerative diseases associated with intracytosolic aggregate formation, like Huntingto...

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Detalhes bibliográficos
Main Authors: Winslow, Ashley R., Rubinsztein, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597715/
https://ncbi.nlm.nih.gov/pubmed/18644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.06.010
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