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Autophagy in neurodegeneration and development

Efficient protein turnover is essential for the maintenance of cellular health. Here we review how autophagy has fundamental functions in cellular homeostasis and possible uses as a therapeutic strategy for neurodegenerative diseases associated with intracytosolic aggregate formation, like Huntingto...

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Détails bibliographiques
Auteurs principaux: Winslow, Ashley R., Rubinsztein, David C.
Format: Artigo
Langue:Inglês
Publié: Elsevier Pub. Co 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597715/
https://ncbi.nlm.nih.gov/pubmed/18644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.06.010
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