Autophagy in neurodegeneration and development

Efficient protein turnover is essential for the maintenance of cellular health. Here we review how autophagy has fundamental functions in cellular homeostasis and possible uses as a therapeutic strategy for neurodegenerative diseases associated with intracytosolic aggregate formation, like Huntingto...

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Bibliographic Details
Main Authors: Winslow, Ashley R., Rubinsztein, David C.
Format: Artigo
Language:Inglês
Published: Elsevier Pub. Co 2008
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597715/
https://ncbi.nlm.nih.gov/pubmed/18644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.06.010
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