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Autophagy in neurodegeneration and development

Efficient protein turnover is essential for the maintenance of cellular health. Here we review how autophagy has fundamental functions in cellular homeostasis and possible uses as a therapeutic strategy for neurodegenerative diseases associated with intracytosolic aggregate formation, like Huntingto...

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Autors principals: Winslow, Ashley R., Rubinsztein, David C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Pub. Co 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597715/
https://ncbi.nlm.nih.gov/pubmed/18644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.06.010
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