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Autophagy in neurodegeneration and development

Efficient protein turnover is essential for the maintenance of cellular health. Here we review how autophagy has fundamental functions in cellular homeostasis and possible uses as a therapeutic strategy for neurodegenerative diseases associated with intracytosolic aggregate formation, like Huntingto...

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Detalles Bibliográficos
Main Authors: Winslow, Ashley R., Rubinsztein, David C.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Pub. Co 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597715/
https://ncbi.nlm.nih.gov/pubmed/18644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.06.010
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